Continuous Glucose Monitoring

A Restorative Approach to Nerve Health

Neuropathy

At James Clinic, we view neuropathy not just as “nerve damage,” but as a systemic problem of metabolism, circulation, and cellular energy that can often be improved.

Chesterfield, MO · Ankeny, IA · Chariton, IA · Virtual visits available

What is Neuropathy?

Neuropathy means your peripheral nerves are not working properly. This can cause:

Numbness or tingling
Burning, electric, or stabbing pain
Loss of sensation
Balance problems
Weakness
Temperature sensitivity
Slow wound healing

Common Causes of Neuropathy

Neuropathy can develop from many causes, including:

Diabetes or Insulin Resistance (Most Common)

High or fluctuating blood sugar impairs:

Blood flow to nerves
Energy production inside nerve cells
Nutrient delivery to nerve tissue

Over time, this leads to nerve dysfunction.

Chemotherapy-Induced Neuropathy

Some chemotherapy drugs damage nerves through:

Oxidative stress
Mitochondrial injury
Microvascular (small vessel) damage

Symptoms may include burning, numbness, or sensitivity in hands and feet.

Post–COVID or Post-Viral Neuropathy

After infections like COVID-19, some people develop neuropathy due to:

Persistent inflammation
Immune dysregulation
Microvascular injury
Mitochondrial dysfunction

Other Causes

Neuropathy can also be associated with:

Vitamin deficiencies (especially B12)
Autoimmune disease
Toxin exposure
Alcohol use
Chronic inflammation
“Idiopathic” (unknown cause) neuropathy

Traditional Treatment vs. Our Approach

Standard Medical Treatment (What most patients are offered)

Common medications include:

Gabapentin (Neurontin)
Pregabalin (Lyrica)
Duloxetine (Cymbalta)

These can reduce pain, but they do not repair nerves or restore function. Many patients experience side effects such as drowsiness, dizziness, or brain fog.

Standard care = symptom control, not nerve healing.

The James Clinic Neuropathy Protocol

A Stepwise, Restorative Plan

We focus on repairing the system that supports your nerves, not just masking symptoms.

Neuropathy is often metabolic, microvascular, and mitochondrial — not just structural.

Standard medicine quiets symptoms.
Our approach works to restore nerve health.

Step 1 — Nutrient Restoration (The Foundation)

We optimize the nutrients your nerves need to heal, including:

Vitamin B12, B1, and balanced B6
Folate
Vitamin D
Zinc and magnesium
Adequate protein

We also work on blood sugar and insulin sensitivity, which are critical for nerve recovery.

Step 2 — Alpha Lipoic Acid (ALA) Infusions

ALA is a powerful antioxidant that helps:

Reduce nerve inflammation
Improve energy production in nerve cells
Support nerve function
Reduce burning pain in many patients

We use IV ALA for better absorption and effect.

Step 3 — Platelet-Rich Plasma (PRP)

PRP contains growth factors that help:

Stimulate nerve repair
Reduce chronic inflammation
Improve blood flow to nerves
Support nerve regeneration

This is especially helpful in diabetic or chemotherapy-related neuropathy.

Step 4 — Mitochondrial Reboot with Micro-Dose Infusion (MDI)

Many forms of neuropathy involve energy failure inside nerve cells.

MDI therapy helps:

Restore normal fuel use inside nerves
Improve mitochondrial energy production
Enhance microcirculation
Support long-term nerve repair

This is a restorative, biologic approach—not a pain medication.

What You Can Expect

A comprehensive evaluation of your symptoms and medical history
Personalized sequencing of therapies
Gradual, measurable improvements over time (not overnight)
Close follow-up and adjustments based on your response

Some patients notice early changes in sensation, pain, or stability within weeks, while others improve more gradually.

Who Is This Program For?

This approach is ideal if you have:

Diabetic or prediabetic neuropathy
Chemotherapy-induced neuropathy
Post–COVID neuropathy
Neuropathy with no clear cause
Tried medications without meaningful benefit
A desire for nerve repair, not just pain relief

Resources

Things you can do next

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   Dave Greene 
 
 
 
 Trustindex verifies that the original source of the review is Google. The entire staff is very friendly and sincerely interested your health. I have had blood tests done that my insurance primary has never heard of and that revealed issues that he was unaware of.  James clinic diagnosed the cause and cured tge problem. They are the best!
  
 
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   steven marchant 
 
 
 
 Trustindex verifies that the original source of the review is Google. The James Clinic is like stepping into a different world,they care about their patients! I've been with them several years, it's a five hour drive for me. They seem more like family That's hard to find! I would suggest the James Clinic 100 percent.
  
 
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   Deanna Martin 
 
 
 
 Trustindex verifies that the original source of the review is Google. I love the James Clinic and everyone there! I have learned so much about how to improve my health and not just how to treat my symptoms. They are so real there. They talk to you. They engage on a personal level and really care about my health and wellness. I feel very in control of my healthcare rather than being controlled by the provider or insurance company. I highly recommend this clinic and its providers!!
  
 
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   Maria C 
 
 
 
 Trustindex verifies that the original source of the review is Google. Exceptional from the staff at the front door, throughout the clinic, the advance practice HCPs and Dr. James herself!  Do yourself a favor and make the investment in your OPTIMAL state of health.  Come educated. Come curious.  They love having discussions.  The testing and health optimization tools they offer are exceptional.
  
 
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   Brad Smyth 
 
 
 
 Trustindex verifies that the original source of the review is Google. I cannot say enough positive things about Dr James and her entire staff.  We work primarily with Sara Taylor, NP, and she has been nothing short of amazing.  Our whole family, including my two teenage boys, have been with them for over a year now and we are thankful every day that we found them.  One of my teenage sons has ASD, on top of numerous health issues and the attention Sara and the team has given to help him has been life changing!
  
 
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   Brett & Connie Roberts 
 
 
 
 Trustindex verifies that the original source of the review is Google. Sara Taylor is awesome! She has taken care of all my outpatient needs for more than 18 months! 10/10 all the time
  
 
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   Jennifer Lyman 
 
 
 
 Trustindex verifies that the original source of the review is Google. In addition to being incredibly knowledgable, I really appreciate the care Kate takes with her patients. It's very valuable to me that they are functional medicine physicians/NPs at this practice vs those who wear the doctor title without having medical training.
  
 
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   Joanne Curran 
 
 
 
 Trustindex verifies that the original source of the review is Google. NPs Justina Timms and Sarah Taylor are always incredibly well prepared, knowledgeable and take all the time needed to explain labs and test results to me in ways that I can understand. Their professionalism and expertise continue to astound me. They also check in after procedures or explanations with well documented follow up.  In addition, every nurse at the clinic is warm, friendly, personable, knowledgeable and professional to the Nth degree! Theresa, Michelle, Whitney, Lauren, Brenda, Mary and Chelsea all work hard and are extremely timely when completing procedures such as HBOT and MDI treatments. I have nothing but the highest regard for the James Clinic and all who work there including their lead Dr. Mollie James. My gratitude runs deep for their services.