Conditions We Treat

What's actually going on?
We find out.

Fourteen categories, one approach: real testing, real time, and a physician who won't stop at "your labs are normal."

Chesterfield, MO · Ankeny, IA · Chariton, IA · Virtual visits available

Healing Starts Here

Explore by condition

Chronic & Complex

Cancer

Comprehensive care, from diagnosis to remission, for a wide range of cancer types.

Lyme disease

Tailored strategies to manage Lyme disease, aiming for recovery and restoration of normal life activities.

Dementia & memory

Diagnosis, management, and support for a range of cognitive disorders, including dementia and memory problems.

Metabolic & Weight

Metabolic syndrome

Personalized treatment for managing this cluster of conditions, including high blood pressure, insulin, and abnormal cholesterol levels.

Hormonal imbalances

Addressing a range of hormone-related conditions and helping restore hormonal balance for better health.

Weight loss resistance

Comprehensive assessment and customized weight management plans integrating diet, exercise, and behavioral changes.

Thyroid conditions

Clinical management for a spectrum of thyroid conditions, including hypothyroidism, hyperthyroidism, and thyroid nodules.

Pain, Injury & Performance

Injury & Operative Recovery

Faster, more complete healing after surgery or injury using regenerative and integrative protocols.

Physical Limitations & Musculoskeletal Pain

When pain starts changing how your body functions, it’s no longer just a symptom—it’s a performance problem.

Elite athlete conditions

Specialized care to help elite athletes maintain peak performance and manage sports-related conditions.

Neuropathy

At James Clinic, we view neuropathy not just as “nerve damage,” but as a systemic problem of metabolism, circulation, and cellular energy that can often be improved.

Gut, Wound & Pediatric

Gut & digestion

Focusing on the crucial importance of gut health, providing guidance and treatments to optimize your gut microbiome.

Wound Care

Holistic, patient-centered treatment that promotes faster healing through advanced care, nutrition, hydration, and lifestyle support.

Pediatric PANS/PANDA

Treatment for pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections and nervous system inflammation.

Feel the way you know you could

Imagine a healthcare experience that moves beyond symptom management and one-size-fits-all medicine to uncover the biological truths that shape your wellbeing.

At The James Clinic, we combine sophisticated diagnostics with bespoke therapeutic protocols to restore energy, resilience, and performance at the deepest levels.

Root-cause approach

With our expertise in integrative and functional medicine, we understand how your body functions on multiple levels. Before turning to medications or surgery, find out what your body truly needs right now.

Advanced modalities
We use a range of regenerative therapies to enhance tissue healing, including injections and infusions, that foster the body’s innate ability to heal itself naturally.

Which sounds like you?

Two doors. One promise: real answers, from physicians with the time to find them.

Chronic & Complex

You've been searching for answers

Conditions that conventional medicine has struggled to explain or resolve — cancer, Lyme, dementia, unexplained pain.

Start Here

Performance & Prevention

You want to stay ahead of it

Conditions caught early or optimized proactively — metabolic health, hormone balance, athletic performance.

Start Here

HOW IT WORKS

Resources

Things you can do next

Request an Appointment

Start an appointment request with James Clinic.

Check Our Locations

See where our clinics are located and the states we serve.

Frequently Asked Questions

What you need to know about working with us.

      EXCELLENT  
   Based on 63 reviews 
    
 
 
 
   
 
 
       Posted on Google  
   
   Dave Greene 
 
 
 
 Trustindex verifies that the original source of the review is Google. The entire staff is very friendly and sincerely interested your health. I have had blood tests done that my insurance primary has never heard of and that revealed issues that he was unaware of.  James clinic diagnosed the cause and cured tge problem. They are the best!
  
 
      Posted on Google  
   
   steven marchant 
 
 
 
 Trustindex verifies that the original source of the review is Google. The James Clinic is like stepping into a different world,they care about their patients! I've been with them several years, it's a five hour drive for me. They seem more like family That's hard to find! I would suggest the James Clinic 100 percent.
  
 
      Posted on Google  
   
   Deanna Martin 
 
 
 
 Trustindex verifies that the original source of the review is Google. I love the James Clinic and everyone there! I have learned so much about how to improve my health and not just how to treat my symptoms. They are so real there. They talk to you. They engage on a personal level and really care about my health and wellness. I feel very in control of my healthcare rather than being controlled by the provider or insurance company. I highly recommend this clinic and its providers!!
  
 
      Posted on Google  
   
   Maria C 
 
 
 
 Trustindex verifies that the original source of the review is Google. Exceptional from the staff at the front door, throughout the clinic, the advance practice HCPs and Dr. James herself!  Do yourself a favor and make the investment in your OPTIMAL state of health.  Come educated. Come curious.  They love having discussions.  The testing and health optimization tools they offer are exceptional.
  
 
      Posted on Google  
   
   Brad Smyth 
 
 
 
 Trustindex verifies that the original source of the review is Google. I cannot say enough positive things about Dr James and her entire staff.  We work primarily with Sara Taylor, NP, and she has been nothing short of amazing.  Our whole family, including my two teenage boys, have been with them for over a year now and we are thankful every day that we found them.  One of my teenage sons has ASD, on top of numerous health issues and the attention Sara and the team has given to help him has been life changing!
  
 
      Posted on Google  
   
   Brett & Connie Roberts 
 
 
 
 Trustindex verifies that the original source of the review is Google. Sara Taylor is awesome! She has taken care of all my outpatient needs for more than 18 months! 10/10 all the time
  
 
      Posted on Google  
   
   Jennifer Lyman 
 
 
 
 Trustindex verifies that the original source of the review is Google. In addition to being incredibly knowledgable, I really appreciate the care Kate takes with her patients. It's very valuable to me that they are functional medicine physicians/NPs at this practice vs those who wear the doctor title without having medical training.
  
 
      Posted on Google  
   
   Joanne Curran 
 
 
 
 Trustindex verifies that the original source of the review is Google. NPs Justina Timms and Sarah Taylor are always incredibly well prepared, knowledgeable and take all the time needed to explain labs and test results to me in ways that I can understand. Their professionalism and expertise continue to astound me. They also check in after procedures or explanations with well documented follow up.  In addition, every nurse at the clinic is warm, friendly, personable, knowledgeable and professional to the Nth degree! Theresa, Michelle, Whitney, Lauren, Brenda, Mary and Chelsea all work hard and are extremely timely when completing procedures such as HBOT and MDI treatments. I have nothing but the highest regard for the James Clinic and all who work there including their lead Dr. Mollie James. My gratitude runs deep for their services.