FEEL BETTER NOW
What Would Happen If We Could Unlock the Best Version of You?
Integrative medicine that finds the root cause — at a clinic where everybody knows your name.
Chesterfield, MO · Ankeny, IA · Chariton, IA · Virtual visits available
Start Here
Which sounds like you?
Two doors. One promise: real answers, from physicians with the time to find them.
I’M SICK – AND NOT GETTING ANSWERS
We hear you
You’ve been dismissed, rushed, or told “your labs are normal” while you still feel terrible. We take the time conventional medicine can’t.
I’M WELL – AND I WANT MORE
Optimal Performance
You’re healthy and you intend to stay that way. Measure what matters, optimize what’s possible, and add good years to your life.
Healing Starts Here
Learn more about the conditions we specialize in and the treatments that support healing.
Diverse range of treatments that promote tissue regeneration to let the body heal itself.
Explore the conditions that our functional medicine doctors treat.
Practitioner-grade supplements that we use in practice, available to you.
Proactive, preventative health care that is personalized to you.
Three clinics in the United States and virtual options for you to choose from.
Our Promise
Medicine where everybody
knows your name.
Walk in and you’re greeted like a neighbor. Your physician knows your story, your goals, and your name — and answers directly to you.
Dedicated Pathways
Some journeys deserve their own map.
Hormone Health
Bioidentical hormone therapy for women and men — energy, mood, sleep, libido, and longevity, restored with precision testing.
Terrain Oncology
Integrative cancer support that works alongside your oncology team — strengthening the terrain your body fights from.
Pediatrics
From PANS/PANDAS and chronic illness to proactive wellness — whole-child medicine with time to actually listen.
Patients don't just get seen here.
They get better.
of patients see measurable improvement within the first three months of care
health indicators analyzed to find the root cause — not just the symptom
would recommend James Clinic to their family and friends
Our Story
Where everybody knows your name.
Dr. Mollie James trained as a trauma surgeon and critical care physician — the doctor you’d want in the worst moment of your life. But she dreamed of a different kind of clinic: one that fills the gaps conventional medicine leaves behind. A place where you’re greeted like a neighbor, your story is actually heard, and your physician is directly accountable to you — not to an insurance company.
That clinic exists. Three of them, actually
Dr. Mollie James, DO, MPH, IFMCP
Founder, James Clinic
Feel Better Now
It starts with a conversation — free, unhurried, and honest.
Chesterfield, MO · Ankeny, IA · Chariton, IA · Virtual
EXCELLENT Based on 59 reviews Posted on Google Jennifer LymanTrustindex verifies that the original source of the review is Google. In addition to being incredibly knowledgable, I really appreciate the care Kate takes with her patients. It's very valuable to me that they are functional medicine physicians/NPs at this practice vs those who wear the doctor title without having medical training.Posted on Google Joanne CurranTrustindex verifies that the original source of the review is Google. NPs Justina Timms and Sarah Taylor are always incredibly well prepared, knowledgeable and take all the time needed to explain labs and test results to me in ways that I can understand. Their professionalism and expertise continue to astound me. They also check in after procedures or explanations with well documented follow up. In addition, every nurse at the clinic is warm, friendly, personable, knowledgeable and professional to the Nth degree! Theresa, Michelle, Whitney, Lauren, Brenda, Mary and Chelsea all work hard and are extremely timely when completing procedures such as HBOT and MDI treatments. I have nothing but the highest regard for the James Clinic and all who work there including their lead Dr. Mollie James. My gratitude runs deep for their services.Posted on Google Mark YorkTrustindex verifies that the original source of the review is Google. Cutting edge technology. Highly trained and professional staff who love to serve. They are FRIENDLY too! Cured my cancer and making great progress on diabetes. The only way you can go wrong is to not give these folks a shot!Posted on Google Stephen NewlonTrustindex verifies that the original source of the review is Google. I used to be super active — then COVID hit, and everything fell apart. I felt blindsided. My life shrank to the floor, and walking to the kitchen became a challenge. I had health insurance, but no real care. After searching online, I found Dr. James. She offered something I desperately needed: hope — and just as importantly, genuine understanding. We tried different approaches, I improved a little, and I began to accept that this might just be my new normal. But Dr. James didn't give up. She researched, consulted colleagues, and kept pushing. No doctor had ever invested that much effort in helping me. Then one day, she mentioned MDI. I was skeptical, but willing to try. Eight sessions later, I have my life back. That's not an overstatement — imagine going from barely existing to truly living again. The road to recovery isn't easy, especially given everything we're up against today. But I'm back, and it's because of Dr. James.Posted on Google Susan FosterTrustindex verifies that the original source of the review is Google. Dr. james and the entire staff show such compassion and genuinely care for their patients. We are so thankful for the time they spend on our treatment plans, as well as the knowledge they have. Always give us hope. Blessed to have them as part of our medical team!!!Posted on Google Michelle HarrellTrustindex verifies that the original source of the review is Google. I love being able to go to the James Clinic and they have been a blessing to me over the last 3 years. Everyone there really listens to you and is always respectful. This is how medicine should be and is hopefully changing the status quo going forward. They are very interested in getting to the root cause of your symptoms and offering outside of the box treatments that I would never have been offered from conventional medicine.Posted on Google Jessica OTrustindex verifies that the original source of the review is Google. When I was diagnosed with cancer summer of 2025, my sister found out about the James Clinic. I called and got myself set up and they were so helpful! Whenever I have had a question or issue with anything Dr. James and her staff respond back quickly which is very much appreciated! I have been getting hbot and IV therapy for 7 months now. The past 3.5 months I have been going through conventional treatment and I repeatedly get told by the oncologist on how well I am doing. Also, a big shout out to the clinic IV nurses they have been fantastic! I am so very thankful to have the James Clinic supporting me through this diagnosis.Posted on Google Angela NorrisTrustindex verifies that the original source of the review is Google. The James Clinic team is phenomenal! After searching for years for a physician to assist me in getting to the root of my underlying condition, I finally found Sarah at James Clinic. Their clinic approach is whole person and patient centered which allows for individualized care. It is very empowering because you are heard and part of the healing process.Posted on Google Melissa IahnTrustindex verifies that the original source of the review is Google. I cannot praise Dr. James and her incredible staff enough! This is the only practice that has truly listened to my concerns, truthfully considered treatments/benefits/risks, and honored my personal health goals all while considering my lifestyle preferences when treating my health. I am grateful to have such a supportive and encouraging doctor who truly cares about my wellness! Everyone should have a doctor as caring as Dr. James to help them make the most important choices about their health!