About The James Clinic
Not just another integrative medicine clinic.
A precision medicine powerhouse
Advanced functional testing, cutting-edge mitochondrial reboot therapies, and proactive medical strategies to redefine what health can look like.
Chesterfield, MO · Ankeny, IA · Chariton, IA · Virtual visits available
Our Story
Filling the Gaps in Conventional Medicine
The James Clinic was founded out of a desire to create a healthcare experience that truly caters to the individual. Years ago, Dr. Mollie James, a board-certified surgeon and critical care specialist, noticed the gaps in conventional medicine and envisioned a place where patients could receive both functional and integrative care.
Today, our clinic combines functional medicine with cutting-edge regenerative therapies to offer natural solutions to help your body heal itself. Whether you’re facing chronic health challenges or looking to optimize your wellness, we help you find the answers you need.
Who We Are
Medicine where everybody
knows your name.
At The James Clinic, we believe in a patient-centered approach that goes beyond the traditional healthcare model. As a premier functional medicine clinic, we understand how your body functions on multiple levels, and we use this knowledge to empower you to take charge of your health.
Our clinic offers personalized care with the warmth and attention that modern healthcare often lacks. Here, you’re not just a patient — you’re part of our family.
Experience the Small-Town Feel in Modern Healthcare
One of the things that sets The James Clinic apart is our ability to combine modern medicine with a welcoming, small-town atmosphere. Our patients experience healthcare that’s cutting-edge and deeply compassionate.
When you step into our clinic, you’ll find a team that genuinely cares about your well-being and is dedicated to helping you heal. This is healthcare the way it should be — personal, effective, and centered on you.
"This is healthcare the way it should be — personal, effective, and centered on you."
Our Mission & Values
Healthcare that empowers long-term wellness
Our mission is simple: to provide accessible, compassionate, and effective healthcare that empowers you to lead a healthier life. At The James Clinic, we don’t just treat symptoms — we uncover the root causes of your health concerns and develop a plan that focuses on long-term wellness.
By integrating functional medicine with advanced regenerative treatments, we help you address your health holistically.
Integrity
We are transparent in everything we do, with no insurance interference in the doctor–patient relationship.
Patient Empowerment
We give you the knowledge, testing, and strategies to take real control of your health journey.
Transparency
No hidden costs, no rushed visits. You work directly with us and we are directly accountable to you.
Our Team
Meet Your Functional Medicine Doctors
Led by Dr. Mollie James, our functional medicine doctors bring years of medical expertise and a passion for integrative healthcare to our clinic. They focus on personalized treatments that address the unique needs of each patient.
Meet our functional medicine practitioners now.
The Apothecary
Medicine you can trust, from people you know
Before medicine became an industry, your pharmacist knew your name.
The Apothecary brings that back — practitioner-grade supplements, peptides, and formulations we use in our own practice, held to clinical standards and delivered to your door.
- The exact brands and dosing we prescribe in clinic
- Third-party tested — no fillers, no guesswork
- Curated by our physicians, not an algorithm
Faq
Do You Take Insurance?
At The James Clinic, we believe in a patient-centered approach that goes beyond the traditional healthcare model. As a premier functional medicine clinic, we understand how your body functions on multiple levels, and we use this knowledge to empower you to take charge of your health.
No one who’s serious about transforming their health believes insurance is the solution to their problems. While premiums continue to rise, most insurance-based care is built around rushed visits, limited thinking, and reactive treatment. The true costs are often hidden: fragmented care, missed root causes, and years spent managing symptoms instead of solving problems.
At James Clinic, we do not allow insurance to interfere with the doctor–patient relationship. There is no third party dictating how long we spend with you, what we can test, or how deeply we can think. You work directly with us, and we are directly accountable to you.
Each visit with our team is the equivalent of 12 to 15 standard 7-minute medical appointments. We take the time to review your full history, analyze advanced testing, connect patterns, and build a comprehensive, personalized strategy. That level of depth is impossible in conventional, insurance-driven care.
Our patients consistently tell us that while this model requires an upfront investment, it saves them time, frustration, and money in the long run by reducing unnecessary medications, avoiding missed diagnoses, and creating real, lasting progress.
This is medicine designed for people who want answers, strategy, and transformation, not just a quick prescription and a pat on the back.
Things you can do next
Request an Appointment
Start an appointment request with James Clinic and begin your healthcare journey.
Check Our Locations
See where our clinics are located and the states we serve, including virtual visits.
Frequently Asked Questions
What you need to know about working with us, appointments, and our approach.
Start healing with the right answers
Connect with our patient advisor to learn what the best treatment options are for you.
EXCELLENT Based on 59 reviews Posted on Google Jennifer LymanTrustindex verifies that the original source of the review is Google. In addition to being incredibly knowledgable, I really appreciate the care Kate takes with her patients. It's very valuable to me that they are functional medicine physicians/NPs at this practice vs those who wear the doctor title without having medical training.Posted on Google Joanne CurranTrustindex verifies that the original source of the review is Google. NPs Justina Timms and Sarah Taylor are always incredibly well prepared, knowledgeable and take all the time needed to explain labs and test results to me in ways that I can understand. Their professionalism and expertise continue to astound me. They also check in after procedures or explanations with well documented follow up. In addition, every nurse at the clinic is warm, friendly, personable, knowledgeable and professional to the Nth degree! Theresa, Michelle, Whitney, Lauren, Brenda, Mary and Chelsea all work hard and are extremely timely when completing procedures such as HBOT and MDI treatments. I have nothing but the highest regard for the James Clinic and all who work there including their lead Dr. Mollie James. My gratitude runs deep for their services.Posted on Google Mark YorkTrustindex verifies that the original source of the review is Google. Cutting edge technology. Highly trained and professional staff who love to serve. They are FRIENDLY too! Cured my cancer and making great progress on diabetes. The only way you can go wrong is to not give these folks a shot!Posted on Google Stephen NewlonTrustindex verifies that the original source of the review is Google. I used to be super active — then COVID hit, and everything fell apart. I felt blindsided. My life shrank to the floor, and walking to the kitchen became a challenge. I had health insurance, but no real care. After searching online, I found Dr. James. She offered something I desperately needed: hope — and just as importantly, genuine understanding. We tried different approaches, I improved a little, and I began to accept that this might just be my new normal. But Dr. James didn't give up. She researched, consulted colleagues, and kept pushing. No doctor had ever invested that much effort in helping me. Then one day, she mentioned MDI. I was skeptical, but willing to try. Eight sessions later, I have my life back. That's not an overstatement — imagine going from barely existing to truly living again. The road to recovery isn't easy, especially given everything we're up against today. But I'm back, and it's because of Dr. James.Posted on Google Susan FosterTrustindex verifies that the original source of the review is Google. Dr. james and the entire staff show such compassion and genuinely care for their patients. We are so thankful for the time they spend on our treatment plans, as well as the knowledge they have. Always give us hope. Blessed to have them as part of our medical team!!!Posted on Google Michelle HarrellTrustindex verifies that the original source of the review is Google. I love being able to go to the James Clinic and they have been a blessing to me over the last 3 years. Everyone there really listens to you and is always respectful. This is how medicine should be and is hopefully changing the status quo going forward. They are very interested in getting to the root cause of your symptoms and offering outside of the box treatments that I would never have been offered from conventional medicine.Posted on Google Jessica OTrustindex verifies that the original source of the review is Google. When I was diagnosed with cancer summer of 2025, my sister found out about the James Clinic. I called and got myself set up and they were so helpful! Whenever I have had a question or issue with anything Dr. James and her staff respond back quickly which is very much appreciated! I have been getting hbot and IV therapy for 7 months now. The past 3.5 months I have been going through conventional treatment and I repeatedly get told by the oncologist on how well I am doing. Also, a big shout out to the clinic IV nurses they have been fantastic! I am so very thankful to have the James Clinic supporting me through this diagnosis.Posted on Google Angela NorrisTrustindex verifies that the original source of the review is Google. The James Clinic team is phenomenal! After searching for years for a physician to assist me in getting to the root of my underlying condition, I finally found Sarah at James Clinic. Their clinic approach is whole person and patient centered which allows for individualized care. It is very empowering because you are heard and part of the healing process.Posted on Google Melissa IahnTrustindex verifies that the original source of the review is Google. I cannot praise Dr. James and her incredible staff enough! This is the only practice that has truly listened to my concerns, truthfully considered treatments/benefits/risks, and honored my personal health goals all while considering my lifestyle preferences when treating my health. I am grateful to have such a supportive and encouraging doctor who truly cares about my wellness! Everyone should have a doctor as caring as Dr. James to help them make the most important choices about their health!