Expedited Wound Healing
Ozone IV Therapy for Detox & Wellness
Ozone therapy is highly versatile because it optimizes the body's fundamental systems. Much like exercise, which benefits almost all aspects of health, ozone therapy supports the body’s natural processes. 
Chesterfield, MO · Ankeny, IA · Chariton, IA · Virtual visits available

Overview

Ozone Therapy, often called Major Autohemotherapy (MAH), is an advanced treatment where your blood is infused with medical-grade ozone gas, significantly increasing its oxygen content. The process involves withdrawing blood, enriching it with ozone, and reinfusing it, resulting in brighter, oxygen-rich blood re-entering your system. Originating from innovations by Nikola Tesla, this therapy is commonly used for:

  • Lyme disease and mold toxicity.
  • Autoimmune conditions, cardiac issues, and liver diseases.
  • Type 2 diabetes, peripheral artery disease, and chronic heart failure.
  • Prepares patients for antiviral therapy, chemotherapy, or antibiotics.

This increased oxygenation  aids in fighting infections and stimulates the release of growth factors, promoting healing and regeneration throughout the body.

Why it's done

Ozone therapy is highly versatile because it optimizes the body’s fundamental systems. Much like exercise, which benefits almost all aspects of health, ozone therapy supports the body’s natural processes. 
Research shows that ozone therapy can selectively improve blood flow and oxygen delivery to hypoxic brain regions while calming or boosting the immune system, depending on its needs. The therapy doesn’t act directly; instead, it catalyzes the body’s inherent intelligence, helping it function optimally. This adaptability makes ozone therapy beneficial for a wide range of conditions, including:
  • Reducing inflammation
  • Boosting the immune system
  • Improving circulation
  • Providing pain relief
  • Fighting infection
  • Enhancing cellular energy 
  • Increasing energy levels
  • Improving mental clarity

Risks

Ozone therapy is generally safe, but some risks exist, particularly for individuals with a high burden of infections. The primary concern is the Herxheimer reaction, where the immune system rapidly kills off pathogens, releasing toxins that can cause temporary symptoms like headaches, nausea, and fatigue. This reaction can be managed by starting with a lower dose and gradually increasing it.

Other potential side effects include therapy anxiety, especially when seeing blood, fatigue from excessive ozone exposure, and headaches. Careful dose management and post-treatment support can help minimize these risks.

How you prepare

You will start with an initial consultation with one of our clinicians experienced in this therapy. This session will involve a detailed discussion of your medical history, current health status, and any specific health concerns. This will determine whether major autohemotherapy is suitable for your individual needs.

The week before treatment, it’s recommended to increase your daily water intake to one liter, exceeding the usual 64 ounces. To maximize your treatment results, you’ll also receive specific nutrient and antioxidant support before, during, and after the therapy. Make sure to eat a meal beforehand, and inform your provider if you have any allergies or are taking prescription medications.

What you can expect

During major autohemotherapy

You might experience a slight burning sensation when ozone is administered, but this is normal and usually subsides within minutes. We closely monitor your progress and make timely adjustments as needed to optimize your outcomes.

After major autohemotherapy

The entire procedure is typically well-tolerated by patients, but you may experience some nausea, headaches, and vomiting. Some feel the effects of this therapy immediately, while for others, it might take up to a week. There’s no downtime after the treatment, so you can return to work and other daily activities right away.

Results

The number of treatments you need will vary based on the condition you’re addressing and the outcomes you’re aiming for. Each session costs $390. Initially, we typically recommend a ‘loading dose’ of 2-3 sessions per week during the first week of therapy, followed by at least 3 additional sessions to start experiencing the benefits. 

While ozone therapy is highly effective, it rarely works optimally as a standalone treatment. Significant healing results are best achieved when combined with a comprehensive integrative treatment plan. Specifics regarding the frequency and duration of your treatment can be tailored during your initial consultation with your provider.

Frequently asked questions

We have the information you need about Ozone therapy and the common questions we answer for our patients.

Ozone Therapy is a highly specialized medical procedure requiring advanced equipment for administration. Our practitioners are well-versed in its application and closely monitor patients throughout the process. We tailor the use of ozone therapy to individual medical symptoms and diagnoses, ensuring it is prescribed only when it is most appropriate for the patient’s specific needs.

IV Ozone therapy, commonly known as 10-pass or Major Autohemotherapy (MAH), involves removing blood, mixing it with ozone, and then reinfusing it back into the body. This method infuses ozone into the blood but does not filter it.

In contrast, EBOO (Extracorporeal Blood Oxygenation and Ozonation) not only infuses blood with ozone but also filters it. EBOO handles a much larger volume of blood, equivalent to 40 passes of MAH in a single session. The filtration process removes plaque, biofilm, and endotoxins while continuously infusing ozone, ensuring every red blood cell is enriched with ozone.

When administered by a certified healthcare practitioner, ozone therapy is extremely safe with minimal side effects. A study titled “Accident and Typical Complications in Ozone Therapy” reported a complication rate of 0.0007% out of 5.5 million treatment sessions involving 384,775 patients, which translates to roughly 1 in every 150,000 patients treated. Most major complications arose from direct IV injection of ozone, a method not commonly used.
 
However, inhaling ozone gas can cause airway hyper-reactivity, inflammation, and significantly worsen conditions like COPD. Ozone therapy is not recommended for individuals with glucose-6-phosphate dehydrogenase deficiency, uncontrolled hyperthyroidism, during the first three months of pregnancy, and in certain other conditions.

During your consultation, one of our clinicians will discuss whether ozone therapy is safe and appropriate for you. We use universal safety precautions and a well-ventilated exam room to ensure patient safety.

"I've been dealing with chronic fatigue and frequent infections for years. After starting MAH at The James Clinic, I noticed a significant improvement in my overall health. The treatments helped boost my energy levels and immune system, and I felt more resilient against infections. I highly recommend this therapy for anyone struggling with similar issues."

Samantha L. IV Ozone patient

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Dave Greene
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The entire staff is very friendly and sincerely interested your health. I have had blood tests done that my insurance primary has never heard of and that revealed issues that he was unaware of. James clinic diagnosed the cause and cured tge problem. They are the best!
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steven marchant
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The James Clinic is like stepping into a different world,they care about their patients! I've been with them several years, it's a five hour drive for me. They seem more like family That's hard to find! I would suggest the James Clinic 100 percent.
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Deanna Martin
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I love the James Clinic and everyone there! I have learned so much about how to improve my health and not just how to treat my symptoms. They are so real there. They talk to you. They engage on a personal level and really care about my health and wellness. I feel very in control of my healthcare rather than being controlled by the provider or insurance company. I highly recommend this clinic and its providers!!
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Maria C
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Exceptional from the staff at the front door, throughout the clinic, the advance practice HCPs and Dr. James herself! Do yourself a favor and make the investment in your OPTIMAL state of health. Come educated. Come curious. They love having discussions. The testing and health optimization tools they offer are exceptional.
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Brad Smyth
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I cannot say enough positive things about Dr James and her entire staff. We work primarily with Sara Taylor, NP, and she has been nothing short of amazing. Our whole family, including my two teenage boys, have been with them for over a year now and we are thankful every day that we found them. One of my teenage sons has ASD, on top of numerous health issues and the attention Sara and the team has given to help him has been life changing!
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Brett & Connie Roberts
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Sara Taylor is awesome! She has taken care of all my outpatient needs for more than 18 months! 10/10 all the time
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Jennifer Lyman
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In addition to being incredibly knowledgable, I really appreciate the care Kate takes with her patients. It's very valuable to me that they are functional medicine physicians/NPs at this practice vs those who wear the doctor title without having medical training.
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Joanne Curran
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NPs Justina Timms and Sarah Taylor are always incredibly well prepared, knowledgeable and take all the time needed to explain labs and test results to me in ways that I can understand. Their professionalism and expertise continue to astound me. They also check in after procedures or explanations with well documented follow up. In addition, every nurse at the clinic is warm, friendly, personable, knowledgeable and professional to the Nth degree! Theresa, Michelle, Whitney, Lauren, Brenda, Mary and Chelsea all work hard and are extremely timely when completing procedures such as HBOT and MDI treatments. I have nothing but the highest regard for the James Clinic and all who work there including their lead Dr. Mollie James. My gratitude runs deep for their services.

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Chesterfield, MO · Ankeny, IA · Chariton, IA · Telehealth

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