If you’ve been told it’s all in your head, you’re in the right place. We believe you — and we have a path.
“My tests came back negative, so they stopped looking — but I know something is wrong.”
“I’ve tried five different protocols from five different people and feel worse, not better.”
“The fatigue, the pain, the brain fog — it moves around my body and nobody can explain it.”
“I’d have to fly across the country to find a doctor who even treats this.”
The bacteria shelter inside cells, slip into biofilms, and shift forms — evading antibiotics that only reach them part of the time.
Tick bites often deliver co-infections — Bartonella, Babesia, and others — that mask each other and resist treatment differently.
Chronic infection exhausts the immune system, drives inflammation, and depletes the body — so even cleared infections leave you unwell.
Beating Lyme takes more than one drug. It takes a sequence — antimicrobial, oxidative, and restorative — in the right order.
1 in 5
Antimicrobials, ozone, EBOO, HBOT, IV therapy, and restorative medicine — most clinics have one or two. We run the whole sequence in-house.
The same root-cause approach behind our oncology and recovery programs, applied to the most stubborn infection in medicine.
Serious Lyme care has meant traveling to a coast and paying a fortune. We brought it to the Midwest — with telehealth for what doesn’t need a chair.
Tell us your history — every test, every protocol, every dead end. We'll tell you honestly whether Terrain Reset fits.
Comprehensive testing and terrain assessment build the full picture — infection, co-infections, and the systems Lyme has worn down.
Your staged Terrain Reset plan, managed and adjusted by your physician through every phase of recovery.
EXCELLENT Based on 59 reviews Posted on Google Jennifer LymanTrustindex verifies that the original source of the review is Google. In addition to being incredibly knowledgable, I really appreciate the care Kate takes with her patients. It's very valuable to me that they are functional medicine physicians/NPs at this practice vs those who wear the doctor title without having medical training.Posted on Google Joanne CurranTrustindex verifies that the original source of the review is Google. NPs Justina Timms and Sarah Taylor are always incredibly well prepared, knowledgeable and take all the time needed to explain labs and test results to me in ways that I can understand. Their professionalism and expertise continue to astound me. They also check in after procedures or explanations with well documented follow up. In addition, every nurse at the clinic is warm, friendly, personable, knowledgeable and professional to the Nth degree! Theresa, Michelle, Whitney, Lauren, Brenda, Mary and Chelsea all work hard and are extremely timely when completing procedures such as HBOT and MDI treatments. I have nothing but the highest regard for the James Clinic and all who work there including their lead Dr. Mollie James. My gratitude runs deep for their services.Posted on Google Mark YorkTrustindex verifies that the original source of the review is Google. Cutting edge technology. Highly trained and professional staff who love to serve. They are FRIENDLY too! Cured my cancer and making great progress on diabetes. The only way you can go wrong is to not give these folks a shot!Posted on Google Stephen NewlonTrustindex verifies that the original source of the review is Google. I used to be super active — then COVID hit, and everything fell apart. I felt blindsided. My life shrank to the floor, and walking to the kitchen became a challenge. I had health insurance, but no real care. After searching online, I found Dr. James. She offered something I desperately needed: hope — and just as importantly, genuine understanding. We tried different approaches, I improved a little, and I began to accept that this might just be my new normal. But Dr. James didn't give up. She researched, consulted colleagues, and kept pushing. No doctor had ever invested that much effort in helping me. Then one day, she mentioned MDI. I was skeptical, but willing to try. Eight sessions later, I have my life back. That's not an overstatement — imagine going from barely existing to truly living again. The road to recovery isn't easy, especially given everything we're up against today. But I'm back, and it's because of Dr. James.Posted on Google Susan FosterTrustindex verifies that the original source of the review is Google. Dr. james and the entire staff show such compassion and genuinely care for their patients. We are so thankful for the time they spend on our treatment plans, as well as the knowledge they have. Always give us hope. Blessed to have them as part of our medical team!!!Posted on Google Michelle HarrellTrustindex verifies that the original source of the review is Google. I love being able to go to the James Clinic and they have been a blessing to me over the last 3 years. Everyone there really listens to you and is always respectful. This is how medicine should be and is hopefully changing the status quo going forward. They are very interested in getting to the root cause of your symptoms and offering outside of the box treatments that I would never have been offered from conventional medicine.Posted on Google Jessica OTrustindex verifies that the original source of the review is Google. When I was diagnosed with cancer summer of 2025, my sister found out about the James Clinic. I called and got myself set up and they were so helpful! Whenever I have had a question or issue with anything Dr. James and her staff respond back quickly which is very much appreciated! I have been getting hbot and IV therapy for 7 months now. The past 3.5 months I have been going through conventional treatment and I repeatedly get told by the oncologist on how well I am doing. Also, a big shout out to the clinic IV nurses they have been fantastic! I am so very thankful to have the James Clinic supporting me through this diagnosis.Posted on Google Angela NorrisTrustindex verifies that the original source of the review is Google. The James Clinic team is phenomenal! After searching for years for a physician to assist me in getting to the root of my underlying condition, I finally found Sarah at James Clinic. Their clinic approach is whole person and patient centered which allows for individualized care. It is very empowering because you are heard and part of the healing process.Posted on Google Melissa IahnTrustindex verifies that the original source of the review is Google. I cannot praise Dr. James and her incredible staff enough! This is the only practice that has truly listened to my concerns, truthfully considered treatments/benefits/risks, and honored my personal health goals all while considering my lifestyle preferences when treating my health. I am grateful to have such a supportive and encouraging doctor who truly cares about my wellness! Everyone should have a doctor as caring as Dr. James to help them make the most important choices about their health!
One free, unhurried conversation about your history — and an honest look at the road ahead.
Chesterfield, MO · Ankeny, IA · Chariton, IA · Telehealth
Terrain Reset is an individualized, physician-supervised program of integrative and supportive care. Therapies are used to support the body and overall wellness; individual results vary, and care is tailored to each patient following evaluation. This information is educational and is not a substitute for a medical consultation.
We have established a Venmo where 100% of the donations will go directly to support those without access to medical care. Please consider donating and praying for these families.