Understanding PANS & PANDAS
Parents often find themselves bewildered and distressed when their children suddenly exhibit neurological or psychiatric symptoms following a seemingly minor infection. These symptoms could be indicative of Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS) or Pediatric Autoimmune Neuropsychiatric Disorders (PANDAS).
PANS and PANDAS are conditions triggered by the body’s immune response to an infection. In the process of fighting off the infection, the immune system can mistakenly cause inflammation in the brain, leading to a rapid onset of new and concerning symptoms. At The James Clinic, we specialize in diagnosing and treating these complex conditions to help children regain their health and well-being.
Recognizing the Symptoms
Our Diagnostic & Treatment Philosophy
These conditions, estimated to affect 1 in 200 children, can be challenging to diagnose and require the expertise of experienced healthcare professionals. Here’s a closer look at the data and our approach at The James Clinic:
Age of Onset
PANS and PANDAS can manifest at various ages, though certain age groups are more commonly affected:
- 1 to 3 years: 11% – Symptoms can appear very early, often complicating early childhood development.
- 4 to 9 years: 69% – The majority of cases begin during early childhood, a critical period for neurological and behavioral development.
- 10 to 13 years: 19% – Onset during later childhood can impact school performance and social interactions.
- 14+ years: 1% – Rare but possible, late onset can overlap with other adolescent health issues.
Primary Symptoms
The symptoms of PANS and PANDAS can vary widely, often mimicking other conditions, which makes accurate diagnosis crucial:
- Obsessive compulsive disorder (OCD): 37% – Many children develop sudden, severe OCD, significantly disrupting daily life.
- Tics: 14% – Involuntary movements or vocalizations are common, often causing social and functional difficulties.
- Both: 49% – Nearly half of the children experience a combination of OCD and tics, complicating the clinical picture.
Infections Reported
Infections are a common trigger for PANS and PANDAS, with certain pathogens being more frequently associated:
- Strep: 81% – Group A streptococcal infections are the most common trigger, linking PANDAS specifically to strep infections.
- Other (Mycoplasma, Lyme, etc.): 19% – Other infections, including Mycoplasma pneumoniae and Lyme disease, can also trigger PANS, necessitating a broad diagnostic approach.
Testing
Treatment
Advanced Therapy
PANDAS Disease FAQs
We have the information you need for our PANS/PANDA treatment protocol and the common questions we answer for our patients.
Diagnosing PANS and PANDAS involves a comprehensive assessment that includes a detailed medical history, a physical examination, and specialized diagnostic tests. We look for sudden onset of neuropsychiatric symptoms following an infection, such as OCD, tics, or severe mood changes. Blood tests may be conducted to identify underlying infections or immune responses. Our thorough approach ensures an accurate diagnosis, which is crucial for developing an effective treatment plan.
We offer a holistic and personalized treatment approach for PANS and PANDAS. Our treatment options include lifestyle modifications focusing on diet, sleep, and hydration, as well as supplements and prescription medications tailored to the patient’s needs. We also provide advanced therapies such as IV nutrient therapy, hyperbaric oxygen therapy (HBOT), ozone therapy, and TruDose PRP to reduce inflammation and promote recovery. Each treatment plan is customized to address the unique needs of the patient, ensuring comprehensive care and support.