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The Command Center of the Body
Gut–Brain • Hormones • Weight • Immunity • Metabolism
The Gut–Brain Axis: Two Organs, One System
The Gut as a Hormone & Metabolic Regulator
Hormone Metabolism
The gut plays a critical role in:
- Estrogen metabolism and clearance
- Androgen balance
- Thyroid hormone conversion
- Cortisol signaling
An imbalanced microbiome can lead to:
- Estrogen dominance
- Hormonal cycling issues
- Worsening perimenopause and menopause symptoms
- Thyroid dysfunction
Optimizing hormones without optimizing the gut is incomplete care.
Products & Services
More Information
Weight Regulation & GLP-1 Signaling
GLP-1 is not a drug invention. It is a gut hormone.
Your gut microbiome influences:
- GLP-1 secretion
- Satiety signaling
- Appetite regulation
- Insulin sensitivity
- Metabolic efficiency
Disrupted gut signaling contributes to:
- Weight gain
- Cravings
- Metabolic resistance
- Poor response to diet and exercise
Signs Your Gut May Be Driving Systemic Symptoms
- Brain fog or anxiety
- Weight gain or metabolic resistance
- Hormonal imbalance
- Autoimmune flares
- Chronic fatigue
- Food reactions
- Skin issues
The gut rarely whispers quietly.
It speaks through the whole body.
Conditions We Evaluate &
Treat Through a Systems Lens
We commonly address complex, overlapping gut conditions including:
The Stool Test: Your Integrative Fingerprint
At James Clinic, we consider comprehensive stool testing to be the integrative fingerprint of each patient.
Using Genova Diagnostics GI-Effects® testing, we assess:
- Microbiome composition and diversity
- Pathogenic bacteria, parasites, and yeast
- Inflammatory markers
- Digestive enzyme activity
- Short-chain fatty acid production
- Gut immune activation
- Barrier integrity
Eosinophilic Esophagitis (EoE)
An immune-driven inflammatory condition of the esophagus associated with:
Food sensitivities
Dysphagia
Upper GI inflammation
Gastroesophageal Reflux Disease (GERD)
Often mischaracterized as “too much acid.” True drivers may include:
Impaired motility
Microbiome imbalance
Inflammation
SIBO or dysbiosis
Small Intestinal Bacterial Overgrowth (SIBO)
A disorder of bacterial migration and motility, not just infection.
Associated with:
Bloating and pain
Constipation or diarrhea
Food intolerance
Nutrient malabsorption
Food Sensitivities
Often immune-mediated and microbiome-driven rather than true allergies.
Symptoms may include:
GI distress
Brain fog
Fatigue
Skin reactions
Constipation & Diarrhea
Not merely stool frequency problems, but reflections of:
Nervous system signaling
Microbiome balance
Inflammation
Hormonal influence
Parasite & Pathogen Overgrowth
Can drive:
Chronic inflammation
Nutrient depletion
Autoimmune activation
Persistent GI symptoms
Requires precise identification and targeted protocols.
Our Systems-Based Gut Optimization Process
Gut–Liver Connection & Fatty Liver
The gut and liver operate as a metabolic unit.
Gut dysbiosis contributes to:
- Fatty liver disease
- Insulin resistance
- Chronic inflammation
- Cardiometabolic risk
We evaluate liver health using Echosens FibroScan®, allowing:
- Early detection of fatty liver
- Grading of fibrosis
- Monitoring response to intervention
You cannot fix metabolism without addressing gut–liver signaling.
Step 1: Deep Clinical Intake
- Digestive symptoms
- Brain, mood, and energy patterns
- Weight history
- Hormonal status
- Medication and exposure history
Step 2: Precision Diagnostics
- GI-Effects stool testing
- Breath testing when indicated
- FibroScan® for metabolic liver assessment
- Correlated blood markers
Step 3: Individualized Strategy
We integrate:
- Targeted antimicrobial or botanical therapy
- Microbiome rebuilding protocols
- Gut barrier repair
- GLP-1 and satiety support
- Hormone metabolism optimization
- Nervous system regulation
This is not probiotics for everyone.
Signs Your Gut May Be Driving Systemic Symptoms
- Brain fog or anxiety
- Weight gain or metabolic resistance
- Hormonal imbalance
- Autoimmune flares
- Chronic fatigue
- Food reactions
- Skin issues
The gut rarely whispers quietly. It speaks through the whole body.
Why This Approach Works
We do not isolate symptoms. We map systems.
The gut is:
- A brain regulator
- A hormone metabolizer
- A metabolic controller
- An immune gatekeeper
Treating it as anything less guarantees incomplete outcomes.
Frequently asked questions
We have the information you need for our gut health protocol and the common questions we answer for our patients.
We offer both prescription antimicrobials and herbal treatments for gut health issues. Our approach is personalized to each patient’s needs, and we use advanced diagnostic tests to determine the most effective treatment plan. Whether it’s prescription medications or natural remedies, our goal is to restore and maintain a healthy gut microbiome and overall digestive health.
We offer both in-person and virtual consultations to accommodate our patients’ needs. Through our virtual care options, we can provide comprehensive assessments, personalized treatment plans, and ongoing support regardless of your location.
Yes, we understand that supplements can be costly. Patients who join our Gut Healing Program receive a 10% discount on all supplements in our store with an extra 5-15% on subscription orders. If you can’t find what you’re looking for in our store, our Fullscript account offers a 20% discount on all supplements.